Best known for her portrayal of darker roles and mature content from an early age, Chloë Grace Moretz was born to Teri Duke, a nurse practitioner, and McCoy Moretz, a plastic surgeon, on 10 February 1997 in Atlanta, Georgia, and raised in Cartersville, Georgia. Initially, she attended Laurel Springs School, a fully accredited online school, but as she wished to pursue her career in acting, she was mainly homeschooled by her mother, while her brother, Trevor, who was attending a performing arts high school, acted as her mentor. At the tender age of five, she moved to New York City in 2002, with her mother and brother, as her brother Trevor got the opportunity to study in The Professional Performing Arts School, which also sparked her own interest in acting. However, her Hollywood career began when she and the rest of her family moved to Los Angeles in 2003.

Chloë Grace Moretz got her first break on the TV screen in two episodes of the series The Guardian, in which she appeared as Violet, and her first break on the silver screen was Heart of the Beholder (2005), a drama film, in which she played the role of Molly. However, in her second big-screen acting role, the role of Chelsea Lutz in the remake of the 1979 supernatural horror film The Amityville Horror (2005), she earned greater recognition, receiving a Young Artist Award nomination. After her appearance in Amityville, Moretz appeared in several small roles on TV, as well as in films like Big Momma’s House 2 (2006), and Room 6 (2006), followed by The Third Nail (2007), The Eye (2008), and The Poker House (2008), in which she played the role of Cammie, an abused child.

After appearing in the romantic comedy film 500 Days of Summer (2009) as Rachel, Chloë Grace was trained with Jackie Chan’s stunt crew for three months, for proper preparation for her role as the Hit-Girl, Mindy Macready, in the superhero black comedy action film Kick-Ass (2010), directed by Matthew Vaughn. While filming on location, Chloë Grace did most of her own stunts, and despite the huge controversy surrounding her role in the violent film at that tender age, she earned overwhelming acclaim from the film critics for her stunning performance in the film. Notably, though the famous film critic Roger Ebert gave the film only one star, he specifically highlighted Chloë Grace Moretz’s presence and appeal in the film. The same year, she also portrayed Angie Steadman in the coming-of-age buddy comedy Diary of a Wimpy Kid (2010), and played Abby, a 12-year-old vampire, in Let Me In (2010), the American remake of the Swedish romantic horror film Let the Right One In (2008).

The following year, Chloë Grace played Little Ann Sliger in the psychological thriller Texas Killing Fields (2011), appeared as Luli McMullen, a 13-year-old Nebraskan girl who ran away from her neglectful parents and sets out for Las Vegas, in Hick (2011), and also portrayed the role of Isabelle in historical adventure film Hugo (2011), directed by Martin Scorsese, which was nominated for 11 Oscars. The next year, she appeared as Carolyn Stoddard, a rebellious teenage daughter, in Tim Burton’s horror comedy film Dark Shadows (2012). In 2013, apart from reprising her role as Hit-Girl in Kick-Ass 2 (2013), Grace Moretz appeared in a short segment in the film Movie 43 (2013), and in the supernatural horror film Carrie (2013), in which she portrayed the role of the shy outcast Carrie White, bullied daily by her high school peers and abused by her religious mother Margaret, played by Julianne Moore.

In 2014, Grace Moretz appeared in the award-winning psychological drama film, a French-German-Swiss co-production, Clouds of Sils Maria (2014), which follows an established, middle-aged actress Maria Enders, played by Juliette Binoche, cast as the older lover, in a romantic lesbian drama opposite an upstart young starlet Jo-Ann Ellis, portrayed by Moretz. In the teen romantic drama If I Stay (2014), she played the protagonist Mia Hall, a 17-year-old classical musician in a coma after a car accident, who during an out-of-body experience, must decide whether to wake up and live a life far different than she had imagined. Apart from that, she appeared as Teri, in the vigilante action film The Equalizer (2014), starred as young Diondra in the mystery film Dark Places (2015), appeared as Cassie Sullivan in the science-fiction film The 5th Wave (2016), for which Hannah Minghella of Sony Pictures depicted that Moretz embodied the heart, strength and determination that make Cassie such a compelling character. In 2016, apart from starring in the comedy film Neighbors 2: Sorority Rising (2016), Moretz also headlined the drama film Brain on Fire (2016), based on a true story, in which she convincingly played the lead role of a journalist Susannah Cahalan who suddenly began to experience a mysterious illness and found herself losing her grip on life.

In 2016, Moretz announced that she was re-assessing her choice of roles and was dropping out of several projects, including Universal Studios' film adaptation of The Little Mermaid. Nevertheless, the next year, she co-starred with Ansel Elgort, playing the role of Phoebe in the crime drama November Criminals (2017), and also appeared in that year's controversial comedy-drama I Love You, Daddy (2017), playing the role of China, the aimless 17-year-old daughter of a successful writer, who becomes the interest of an ageing filmmaker with an appalling past. In 2018, Moretz starred in the drama film The Miseducation of Cameron Post (2018), playing the role of Cameron, a teenage girl who is forced into a gay conversion therapy centre by her conservative guardians. The film received positive reviews and has grossed $2 million globally, while Grace Moretz was appreciated for her performance in the film. She next appeared in the horror film Suspiria (2018), which received mixed reviews from critics, and performed poorly at the box office. She then starred opposite Isabelle Huppert in Greta (2018), a thriller film, which follows Frances McCullen, a young waitress, played by Moretz, as she befriends a lonely widow, played by Huppert, who becomes disturbingly obsessed with her. Her other films during the decade include Shadow in the Cloud (2020), an action horror film that follows a female flight officer, Maude Garrett, played by Chloë Grace, on a top-secret mission in the Pacific during the Second World War.

Apart from films, Chloë Grace Moretz has appeared in photo shoots for several fashion magazines, including Flaunt, Vogue, Teen Vogue, Elle and many more. She has publicly supported LGBTQ equality, and identified as a feminist. In her personal life, she was in a relationship with English photographer and former model, Brooklyn Beckham, son of famous former footballer David and English fashion designer, singer, and television personality Victoria Beckham, from 2014 until 2018, when she began dating model Kate Harrison, and in 2024, publicly came out as a gay woman. They confirmed their engagement on 1 January 2025, and were subsequently reported to be married on 1 September 2025.